Condition 1: Hypothyroidism. Condition 2: insulin resistance. Hypothyroidism, unspecified Impaired glucose tolerance (oral)
Conditions
Interventions
Treatment with levothyroxine tablet (Iran hormone) 1.7 micrograms per kg body weight daily for three months.
Sponsors
Tabriz University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: All newly diagnosed hypothyroidism require treatment in the age range of 18 to 65 years
Exclusion criteria
Exclusion criteria: Patients with diabetes mellitus, hypertension, heart failure, liver and kidney disease and polycystic ovary syndrome Treatment with levothyroxine, statins and OCPs in the last 3 months Pregnancy and lactation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Insulin resistance. Timepoint: Baseline, three months after treatment. Method of measurement: Fasting plasma glucose, fasting plasma insulin, HOMA IR(Hemostasis model assessment), QUICKI(Quantitative insulin sensitivity check index). | — |
Secondary
| Measure | Time frame |
|---|---|
| Body mass index. Timepoint: At baseline and three months after treatment. Method of measurement: body weight, height.;Lipid profile. Timepoint: At baseline and three months after treatment. Method of measurement: serum fasting levels of triglycerides, cholesterol, HDL(high density lipoprotein) and LDL(low density lippoprotein). | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Farzad Najafipour
Tabriz University of Medical Sciences
Outcome results
None listed