Comparing different artificial tear drops on post operative ocular discomfort after photorefractive keratectomy.

Comparative study of two artificial tear drops, hyaluronic acid containing artificial tears versus hyaluronic free artificial tears in controlling post surgical eye discomfort following photorefractive keratectomy .

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2013060713567N2

Enrollment

118

Registered

2013-10-03

Start date

2013-10-23

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

hyperopia, myopia. mild or no visual impairment, binocular

Interventions

Intervention 1: For first experimental group, Mitomycin C is used prior to operation, contact lens bandages are used right after surgery and three different eye drops are administered for the followin

Treatment - Drugs

For first experimental group, Mitomycin C is used prior to operation, contact lens bandages are used right after surgery and three different eye drops are administered for the following week: Chloram

For the second experimental group, Mitomycin C is used prior to operation, contact lens bandages are used right after surgery and three different eye drops are administered for the following week: Ch

For the control group, Mitomycin C is used prior to operation, contact lens bandages are used right after surgery and three different eye drops are administered for the following week: Chloramphenico

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Over 18 year of age, Less than 0.5 Diopter change in visual acuity in the previous year, Myopia -1.0 to -6.0, Astigmatism 0.75 to 3.0, Hyperopia +1.0to +4.0, Corneal stroma more than 450 micron, Pupil size less than 6mm. Exclusion criteria: Keratoconus, Herpetic keratitis, Corneal dystrophy, Corneal degeneration, Cataract, Glaucoma, Dry eye, Lag ophthalmos, Uveitis, Blepharitis, diabetes, Pregnancy, Breast feeding, Auto immune disease, Immunodeficiency, History of keloid formation.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Ocular discomfort (including pain, epiphora, foreign body sensation, blurred vision and photophobia). Timepoint: First and fourth day post operation. Method of measurement: Questionnaire.;Visual acuity. Timepoint: On the first, third and sixth month after surgery. Method of measurement: Snelen chart.;Aberrometry. Timepoint: Sixth months after surgery. Method of measurement: Aberrometer.;Corneal haze. Timepoint: On the first, third and sixth month after surgery. Method of measurement: Slit lamp.	—

Measure

Time frame

Ocular discomfort (including pain, epiphora, foreign body sensation, blurred vision and photophobia). Timepoint: First and fourth day post operation. Method of measurement: Questionnaire.;Visual acuity. Timepoint: On the first, third and sixth month after surgery. Method of measurement: Snelen chart.;Aberrometry. Timepoint: Sixth months after surgery. Method of measurement: Aberrometer.;Corneal haze. Timepoint: On the first, third and sixth month after surgery. Method of measurement: Slit lamp.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactMehrdad Mohammadpour

Tehran University of Medical Sciences

mohammadpour_m@sina.tums.ac.ir+98 21 5542 1006

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026