Migraine with aura. Migraine with aura [classical migraine]
Conditions
Interventions
Patients in group 2 received 5 mg/d folic acid for 12 weeks.
Intervention 1: Patients in group 3 received 80 mg/d pyridoxine for 12 weeks. Intervention 2: Patients in group 4 considered as control, received placebo (lactose) for 12 weeks. Intervention 3: patie
Treatment - Drugs
Placebo
Patients in group 3 received 80 mg/d pyridoxine for 12 weeks.
Patients in group 4 considered as control, received placebo (lactose) for 12 weeks.
patients in group 1 received 5 mg/d folic acid and 80 mg/d pyridoxine for 12 weeks
Sponsors
Research Deputy of Isfahan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
15 Years to 65 Years
Inclusion criteria
Inclusion criteria: Patients suffered from migraine in a long time with current diagnosis of MA and a one-year history of severe; recurrent attacks(1 to 8 attacks per month) were selected; The patients with chronic heart disease; previous stroke incidence; chronic renal failure and also with history of taking vitamin B supplements were excluded from the study.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Severity of migraine attacks. Timepoint: First and end of intervention (3 month). Method of measurement: VAS scale.;Frequency of migraine attacks. Timepoint: First and end of intervention (3 month). Method of measurement: Questionnaire.;Duration of migraine attacks. Timepoint: First and end of intervention (3 month). Method of measurement: Questionnaire.;Homocysteine level. Timepoint: First and end of intervention (3 month). Method of measurement: Laboratory analysis ( blood test).;Crp level. Timepoint: First and end of intervention (3 month). Method of measurement: Laboratory analysis ( blood test). | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactOmid Sadeghi
Isfahan University of Medical Sciences
Outcome results
None listed