Skip to content

Investigating the results of adding growth hormone to the ovulation stimulation regimen in microinjection and In Vitro Fertilization in patients with low ovarian reserve

Investigating the results of adding growth hormone to the ovulation stimulation regimen in IVF-ICSI cycles in patients with diminished ovarian reserve

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20130603013566N13
Enrollment
96
Registered
2024-06-17
Start date
2024-06-30
Completion date
Unknown
Last updated
2024-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infertility. Female infertility associated with anovulation

Interventions

Intervention 1: Intervention group: In case group growth hormone will be administered from the mid luteal phase of previous cycle in doses of 8 IU every other days until the HCG administration day in

Sponsors

Vice chancellor for Research,Tabriz University Of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
No minimum to 42 Years

Inclusion criteria

Inclusion criteria: Age less than or equal to 42 years Absence of internal uterine anomalies such as adenomyosis and uterine fibroids and uterine abnormalities and adenomyosis No systemic diseases Consent to study BMI below 30 kg/m2 The number of antral follicles below 5 on the 3rd to 5th days of the menstrual cycle per ovary AMH less than or equal to 1 ng/ml

Exclusion criteria

Exclusion criteria: The recipient of the donor eggs Use of surrogacy Severe impairment of sperm parameters

Design outcomes

Primary

MeasureTime frame
Number of resulted oocytes. Timepoint: The day of oocytes pick up. Method of measurement: Microscopic evaluation.;Quality of resulted oocytes. Timepoint: The day of oocytes pick up. Method of measurement: Microscopic evaluation.;Fertilization rate. Timepoint: Fertilization evaluation will be done between 16 and 20 hours after IVF-ICSI. Method of measurement: Microscopic evaluation.

Secondary

MeasureTime frame
Implantation rate. Timepoint: 4-6 weeks after embryos transfer. Method of measurement: Vaginal sonography.;Chemical pregnancy. Timepoint: Two weeks after pregnancy. Method of measurement: Blood test.;Clinical pregnancy. Timepoint: Two weeks after pregnancy. Method of measurement: Visualization of a pregnancy sac containing a heartbeat on ultrasound.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactKobra Hamdi

Tabriz University of Medical Sciences

lahroudin@gmail.com+98 35519161

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026