Comparison of two methods of estrogen and progesterone hormone administration and endometrial preparation in normal ovarian cycle in endometrial preparation for embryo transfer.

Comparison of freeze embryo transfer cycle results in modified natural cycle versus hormone replacement therapy

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20130603013566N11

Enrollment

150

Registered

2023-03-12

Start date

2023-03-16

Completion date

Unknown

Last updated

2023-04-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infertility. Female infertility associated with anovulation

Interventions

Intervention 1: In the patients of the intervention group, where the preparation of the endometrium will be done by the administration of estrogen and progesterone hormones (artificial or HRT), the 2

Eligibility

Sex/Gender

Female

Age

20 Years to 39 Years

Inclusion criteria

Inclusion criteria: Age between 20 and 39 years Having regular periods History of one failed transfer

Exclusion criteria

Exclusion criteria: Congenital uterine anomalies Uterine fibroids Severe endometriosis Previous history of failed transfer more than twice Endometrial thickness less than 7.5 mm

Design outcomes

Primary

Measure	Time frame
Chemical pregnancy. Timepoint: 14 days after embryo transfer. Method of measurement: HCG ß blood test.;Number of gestational sacs. Timepoint: From week 5 of pregnancy. Method of measurement: Vaginal ultrasound.	—

Secondary

Measure	Time frame
Fetal growth. Timepoint: From the beginning of the intervention to the end of pregnancy. Method of measurement: Ultrasound.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactKobra Hamdi

Tabriz University of Medical Sciences

lahroudin@gmail.com+98 35519161

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026