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Comparison of the effect of GnRH agonist administration with GNRH antagonist protocol on assisted reproductive methods in patients with reduced ovarian response.

Comparison of the effect of gonadotropin-releasing hormone GnRH agonist administration with GNRH antagonist protocol on assisted reproductive methods in patients with reduced ovarian response.

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20130603013566N10
Enrollment
50
Registered
2022-07-31
Start date
2022-08-01
Completion date
Unknown
Last updated
2022-08-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infertility. Female infertility

Interventions

Intervention 1: Control group: In the control group IVF-ICSI with usual GnRH antagonist protocol will be started. Intervention 2: Intervention group: In the case group, patients will receive GNRH agon

Sponsors

Vice chancellor for Research,Tabriz University Of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 42 Years

Inclusion criteria

Inclusion criteria: Infertile women defined as poor ovarian responders according to the Bologna criteria (presence of at least two of the three Bologna criteria) Primary infertility Age 20 to 42

Exclusion criteria

Exclusion criteria: Not agreeing to participate in the study Severe oligospermia body mass index 30 and above Severe endometriosis Smoking and alcohol consumption

Design outcomes

Primary

MeasureTime frame
Number of eggs. Timepoint: the day of oocytes pick up. Method of measurement: Microscopic examination.;Egg quality. Timepoint: The day of oocytes pick up. Method of measurement: Microscopic examination.—

Secondary

MeasureTime frame
Pregnancy. Timepoint: 7-6 weeks to see the gestational sac. Method of measurement: Ultrasound.—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactKobra Hamdi

Tabriz University of Medical Sciences

lahroudin@gmail.com+98 35519161

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026