Treatment results of combined platelet-rich plasma and fat injection in patients with velopharyngeal insufficiency

Treatment results of combined platelet-riched plasma and fat injection in patients with velopharyngeal insufficiency referral to Imam Khomeini Hospital between 2012-2013 years

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT201306018435N5

Enrollment

Registered

2013-06-10

Start date

2012-04-03

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Velopharyngeal insufficiency. Unspecified soft tissue disorder related to use, overuse and pressure

Interventions

combined platelet-rich plasma and fat injection.

Treatment - Other

combined platelet-rich plasma and fat injection

Eligibility

Sex/Gender

All

Age

15 Years to 20 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Patients with repaired cleft palate; Patients aged 15-20 years;Patients with any defects in the pharyngeal wall area and volume;Patients undergoing injection of combined platelet-rich plasma and fat; Patients with mild to moderate velopharyngeal insufficiency confirmed by nasoendoscopy; signing consent to participate in the study. Exclusion criteria: Neurological impairment ; Mental retardation; Tumor area velopharyngeal; Hearing loss; Presence of pharyngeal flap; Oronasal fistula;Large tonsils; Severe velopharyngeal insufficiency.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Gap velopharyngeal. Timepoint: Before the injection, at 6 weeks and 6 months after the injection. Method of measurement: Nasal endoscopy video analysis.;Displacement of the soft palate. Timepoint: Before the injection, at 6 weeks and 6 months after the injection. Method of measurement: Nasal endoscopy video analysis.;Lateral and the posterior pharyngeal wall motion. Timepoint: Before the injection, at 6 weeks and 6 months after the injection. Method of measurement: Nasal endoscopy video analysis.;Hypernasal resonance. Timepoint: Before the injection, at 6 weeks and 6 months after the injection. Method of measurement: Repeat the words and phrases.;Nasal air escape. Timepoint: Before the injection, at 6 weeks and 6 months after the injection. Method of measurement: Repeat the words and phrases.;Intelligibility. Timepoint: Before the injection, at 6 weeks and 6 months after the injection. Method of measurement: Repeat the words and phrases.	—

Measure

Time frame

Gap velopharyngeal. Timepoint: Before the injection, at 6 weeks and 6 months after the injection. Method of measurement: Nasal endoscopy video analysis.;Displacement of the soft palate. Timepoint: Before the injection, at 6 weeks and 6 months after the injection. Method of measurement: Nasal endoscopy video analysis.;Lateral and the posterior pharyngeal wall motion. Timepoint: Before the injection, at 6 weeks and 6 months after the injection. Method of measurement: Nasal endoscopy video analysis.;Hypernasal resonance. Timepoint: Before the injection, at 6 weeks and 6 months after the injection. Method of measurement: Repeat the words and phrases.;Nasal air escape. Timepoint: Before the injection, at 6 weeks and 6 months after the injection. Method of measurement: Repeat the words and phrases.;Intelligibility. Timepoint: Before the injection, at 6 weeks and 6 months after the injection. Method of measurement: Repeat the words and phrases.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactHamid Reza Fathi

Imam Khomeini Hospital

hamifathi@yahoo.com+98 21 6643 8153

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026