oral mucositis. Other and unspecified lesions of oral mucosa
Conditions
Interventions
Intervention 1: From one hour before radio-therapy, patients are given 1% Zataria multiflora mouthwashes, three times daily after breakfast, lunch and dinner for 6 weeks.
Each time patients hold 5
Treatment - Drugs
Placebo
From one hour before radio-therapy, patients are given 1% Zataria multiflora mouthwashes, three times daily after breakfast, lunch and dinner for 6 weeks.
Each time patients hold 5 ml of mouthwas
From one hour before radio-therapy, patients are given placebo (mouthwashes without Zataria multiflora) , three times daily after breakfast, lunch and dinner for 6 weeks.
Each time patients hold
Sponsors
Reasearch & Technology Deputy of Mazandaran medical science
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: Exclusion criteria are: allergy to Zataria multiflora, preexisting oral conditions, pregnancy , use of other medications related to oral mucositis during study period, any systemic diseases interfering with healing. Inclusion criteria: age older than 18 and less than 60 years; newly diagnosed of head and neck cancers; radio-therapy treatment plan with at least 50 Gray exposure doses to oral filed.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Oral mucositis. Timepoint: Every week for 6 weeks. Method of measurement: Oral Mucositis Assessment Scale- OMAS. | — |
Secondary
| Measure | Time frame |
|---|---|
| Pain. Timepoint: Every week for 6 weeks. Method of measurement: Visual analogue pain scale. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAzar Aghamohammadi
Mazandaran University of Medical Sciences
Outcome results
None listed