glaucoma. Primary open-angle glaucoma
Conditions
Interventions
Intervention 1: Control: Including patiens who will receive 0.005% latanoprost eye drops once a day for 6±1 weeks. Intervention 2: Control: including patients who will receive 2% dorzolamide eye drop
Treatment - Drugs
Control: Including patiens who will receive 0.005% latanoprost eye drops once a day for 6±1 weeks.
Control: including patients who will receive 2% dorzolamide eye drops three times a day for 6±1 weeks
Sponsors
Shahid Beheshti University of Medical Sciences
Eligibility
Sex/Gender
All
Age
16 Years to 149 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: all patients with open angle glaucoma; older than 16; with eye pressure of 21 to 30 mm Hg which have not taken any treatment. Exclusion criteria: previous use of systemic or topical dorsolamide; using contact lens since 1 month ago; taking sulfa drug since 1 month ago; lactation; pregnancy (pregnancy reduce eye pressure and increase cornea thickness); cataract; any kind of eye surgery; CD/disc more than 0.8; best visually by less than 20/40 (with using Pin Hole); any neuropathy, any severe damage to visual field; and also any increase in eye pressure more than 30 mm Hg during the study.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Refraction. Timepoint: 2 and 6±1weeks. Method of measurement: Autorefractometr. | — |
Secondary
| Measure | Time frame |
|---|---|
| Visual acuity, thickness of lens and cornea and depth of anterior chamber. Timepoint: 2 and 6±1weeks. Method of measurement: Visual acuity with Snelen chart, thickness of lens and cornea and depth of anterior chamber by IOL Master. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactNarges Moslehi Moghaddam
Shahid Beheshti University of Medical Sciences
Outcome results
None listed