Skip to content

The effects of sufentanil and midazolam combined with bupivacaine on analgesia and complications after cesarean

Comparison of the effects of midazolam and sufentanil combined with intrathecal bupivacaine on the quality of postoperative analgesia and complications in elective cesarean

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT2013052813488N1
Enrollment
75
Registered
2013-11-22
Start date
2012-09-05
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

analgesia after cesarean section. Complications of anaesthesia during labour and delivery

Interventions

Intervention 1: The first group received bupivacaine 0.5% 2.5 ml plus 1 ml of 0.9% normal saline intrathecally. Intervention 2: The second group received bupivacaine 0.5% 2.5ml plus midazolam 0.02mg/
Prevention
The first group received bupivacaine 0.5% 2.5 ml plus 1 ml of 0.9% normal saline intrathecally.
The second group received bupivacaine 0.5% 2.5ml plus midazolam 0.02mg/kg intrathecally.
Third group received 2.5ml bupivacaine 0.5% plus 0.7cc of normal saline 0.9% and 1.5 microgram sufentanil intrathecally.

Sponsors

Vice Chancellor for Research of Semnan Unoversity of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: Inclusion criteria: There was not any contraindication for spinal anesthesia; patients have not any allergy to local anesthetics and other drugs which used in study; patients had not neuropathy. Exclusion criteria: Gastrointestinal disease; premature infants under 36 weeks; use the anti-nausea medication during 24 hours before surgery; hypertension during pregnancy;any problems occur during cesarean section; pain during surgery.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Time to reach the level of anesthesia to T10. Timepoint: every 3 minutes. Method of measurement: Clinical examination.

Secondary

MeasureTime frame
APGAR score, hypotension after surgery, time of pain initiation. Timepoint: after surgery. Method of measurement: Clinical examination.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactRaheleh Azadi

Semnan University of Medical Sciences

azadiraheleh@gmail.com+98 23 1444 1021

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026