Tranexamic acid for treatment of postpartum hemorrhage

The role of tranexamic acid in management of uterine atony during delivery

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2013052613473N1

Enrollment

Registered

2013-07-14

Start date

2012-04-20

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Uterine atony. Other uterine inertia

Interventions

Intervention 1: In the intervention group after uterine Atony, in addition to receiving 30 units of oxytocin within 1 Liter saline,02mg. Methergine IM , uterine massage and ice packs, 1gr trans examic

Treatment - Drugs

In the intervention group after uterine Atony, in addition to receiving 30 units of oxytocin within 1 Liter saline,02mg. Methergine IM , uterine massage and ice packs, 1gr trans examic acid,in the 100

In control group,after uterine Atony only would recevied (30 IU oxytocin in 1 liter of normal saline solution 0.2 mg IM ampoule Methergine and uterine massage and ice packs) .

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: inclusion criteria:all women who were diagnosed as uterine atony by obstetrician following delivery; exclusion criteria:history of any heart disease;liverdisease;kidney disease;history of any hematologic or Thrombophlebitis disease; Thromboembolism disease ;and all women who resieved general anesthesia during delivery.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
The need for surgical intervention. Timepoint: Immediately after the intervention until discharge. Method of measurement: need to hypogastric Artery ligation, uterine artery ligation and hysterectomy based on Surgeon's visual judgment.;Bleeding volume after Atony. Timepoint: Immediatly after Atony. Method of measurement: Per cc and counts gazes and long gazes,and the volume of blood in suction.;Hemoglobin's changes. Timepoint: 6 and 24 hours after bleeding. Method of measurement: gr/dl with Spectrophotometer calibrated.;The need for blood products. Timepoint: After intervention until discharge. Method of measurement: based on unit and signs in surgen's examination or Hemoglobin less than 7.;Hospitalization. Timepoint: after delivery until discharge. Method of measurement: day.	—

Measure

Time frame

The need for surgical intervention. Timepoint: Immediately after the intervention until discharge. Method of measurement: need to hypogastric Artery ligation, uterine artery ligation and hysterectomy based on Surgeon's visual judgment.;Bleeding volume after Atony. Timepoint: Immediatly after Atony. Method of measurement: Per cc and counts gazes and long gazes,and the volume of blood in suction.;Hemoglobin's changes. Timepoint: 6 and 24 hours after bleeding. Method of measurement: gr/dl with Spectrophotometer calibrated.;The need for blood products. Timepoint: After intervention until discharge. Method of measurement: based on unit and signs in surgen's examination or Hemoglobin less than 7.;Hospitalization. Timepoint: after delivery until discharge. Method of measurement: day.

—

Secondary

Measure	Time frame
Nousa/vomiting/thromoamboli. Timepoint: after delivery until release. Method of measurement: examination.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactZoya sadeghipour

Qazvin medical universiyi

zoya7s@yahoo.com+98 28 1223 6374

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026