Determining the effect of Quetiapine on delirium in patients undergoing CABG surgery. Postoperative delirium
Conditions
Interventions
Intervention 1: Intervention group: The group will receive 12.5 mg of oral quetiapine, the first dose on the morning of surgery, then every 12 hours until 48 hours after surgery (25 mg quetiapine ta
Sponsors
Rasht University of Medical Sciences
Eligibility
Sex/Gender
All
Age
35 Years to 85 Years
Inclusion criteria
Inclusion criteria: Elective patients who are candidates for coronary artery bypass surgery 85- 35 years American Society of Anesthesiologists (ASA) II,III GCS 15 to be fully alert and able to communicate
Exclusion criteria
Exclusion criteria: Liver and kidney failure Emergency surgery Confirmation of delirium before ICU admission Patients with a history of mental illness and cognitive behavioral problems before surgery Allergy to quetiapine and its ingredients
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Occurrence of delirium during ICU hospitalization. Timepoint: Daily from the day of surgery until the patient is discharged from the ICU (for 3 days). Method of measurement: CAM- ICU (Confusion Assessment Method for the ICU). | — |
Secondary
| Measure | Time frame |
|---|---|
| Side effects of the drug. Timepoint: Daily. Method of measurement: Observation. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAbbas Sedighinejad
Rasht University of Medical Sciences
Outcome results
None listed