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Effect of hydrogen peroxide oral rinse on incidence of Ventilator-Associated Pneumonia in hospitalized patient in critical care unit

Effect of hydrogen peroxide oral rinse on incidence of Ventilator-Associated Pneumonia in hospitalized patient in critical care unit

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT201305236318N2
Enrollment
15
Registered
2013-06-17
Start date
2013-06-05
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ventilator-Associated Pneumonia. Pneumonitis due to food and vomit

Interventions

Intervention 1: In intervention group, after washing hands and elevation of bed's head and with wear of clear gloves, endo-tracheal tube cuff pressure reached to 25 centimeter of water and then by usi
Prevention
Treatment - Drugs
In intervention group, after washing hands and elevation of bed's head and with wear of clear gloves, endo-tracheal tube cuff pressure reached to 25 centimeter of water and then by using of 4–6 swabs
In control group, after washing hands and elevation of bed's head and with wear of clear gloves, endo-tracheal tube cuff pressure reached to 25 centimeter of water and then by using of 4–6 swabs that

Sponsors

Semnan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Inclusion criteria: more than 18 years old, under mechanical ventilation for more than 48 hours, no signs of aspiration, no pneumonia, no contraindications to oral care, lack of oral trauma, no contraindication to elevation of head of bed at least 30 degrees. Exclusion criteria: if a patient separated from mechanical ventilation for less than 48 hours.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Ventilator-Associated Pneumonia. Timepoint: In 1th and 5th days. Method of measurement: The assessment tool of ventilator-associated pneumonia modified clinical pulmonary infection score, which according to the body temperature, the white blood cell count, tracheal secretions, Ratio of arterial oxygen pressure (Pao2) to inspired oxygen fraction (Fio2) and chest x ray diagnose pneumonia.

Secondary

MeasureTime frame
Ventilator-Associated Pneumonia. Timepoint: In 1th and 5th days. Method of measurement: The assessment tool of ventilator-associated pneumonia modified clinical pulmonary infection score, which according to the body temperature, the white blood cell count, tracheal secretions, Ratio of arterial oxygen pressure (Pao2) to inspired oxygen fraction (Fio2) and chest x ray diagnose pneumonia.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMonir Nobahar

Semnan University of Medical Sciencesl

nobahar43@sem-ums.ac.ir nobahar43@yahoo.com+98 23 1335 4170

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026