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Effect of ultrasound guided intra articular injection of platelet rich plasma(PRP), hyaluronic acid(HA) and combined PRP and HA in patients with hip osteoarthritis

Effect of ultrasound guided intra articular injection of platelet rich plasma(PRP), hyaluronic acid(HA) and combined PRP and HA in patients with hip osteoarthritis

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20130523013442N30
Enrollment
60
Registered
2019-11-29
Start date
2019-06-04
Completion date
Unknown
Last updated
2022-05-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

hip osteoarthritis. Osteoarthritis of hip

Interventions

Intervention 1: Intervention group: platelet rich plasma , hip intraarticular injection, 4 to 6 milliliter, 2 times, 2 weeks interval. Intervention 2: Intervention group: Hyaluronic acid (molecular we

Sponsors

Shahid Beheshti University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 70 Years

Inclusion criteria

Inclusion criteria: Patients with hip osteoarthritis based on American College of Rheumatology criteria at the age of 70-40 years and with the duration of symptoms more than three months that are recognized by hip x-ray (Grade 2 and 3) at the age of 70-40 years duration of symptoms more than three months Grade 2 and 3 recognized by hip x-ray

Exclusion criteria

Exclusion criteria: Systemic diseases such as diabetes mellitus,collagen vascular disorders or immune deficiency History of malignancy Hip infection or active wound History of NSAIDs usage within 2 days before injection Patients who were under anticoagulant or antiplatelet treatments within 10 days before injection Hemoglobin < 12 and plt < 150000 History of severe hip trauma Pregnancy and breastfeeding Allergy to protein of egg , feather or hypersensitivity to hyaluronate

Design outcomes

Primary

MeasureTime frame
Hip pain. Timepoint: before intervention,2 months & 6months after intervention. Method of measurement: changes of WOMAC and VAS and LEQUESNE questionnaires scores.;Joint stiffness. Timepoint: before intervention,2 months & 6 months after intervention. Method of measurement: change of WOMAC questionnaire scores.;Function. Timepoint: before intervention,2 months & 6 months after intervention. Method of measurement: change of WOMAC questionnaire scores.;Activity of daily living. Timepoint: before intervention,2 months & 6 months after intervention. Method of measurement: change of LEQUESNE questionnaire scores.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactParya Peydayesh

Shahid Modarres Hospital

paryapey@gmail.com+98 21 2207 4087

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 11, 2026