Knee osteoarthritis. Osteoarthritis of knee
Conditions
Interventions
Intervention 1: Intervention group 1: plasma rich in growth factor, knee intraarticular injection, 4 to 6 milliliter, 2 times, 3 weeks interval. Intervention 2: Intervention group 2 : Hyaluronic acid
Sponsors
Vice chancellor for research, Shahid Beheshti University of Medical Sciences
Eligibility
Sex/Gender
All
Age
45 Years to 75 Years
Inclusion criteria
Inclusion criteria: Age between 45-75 years Symptomatic knee OA with the pain aggravated by weight bearing Symptoms lasting for at least 6 months despite conservative treatment Kellgren-Lawrance radiology scoring system scores ranging from 2-3
Exclusion criteria
Exclusion criteria: History of trauma , surgery or any invasive procedure in the affected joint during the past 6 months Mal-alignment in lower limbs and abnormal blood count or impared coagulation test Pregnant women Patients who were under immunosuppressant treatments Those with an underlying systemic arthropathy (secondary OA) Patients been treated with angiotensin converting enzyme inhibitors (ACE I) and significant deficiency in glucose 6 - phosphate dehydrogenase (G6PD) level
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Knee Pain. Timepoint: Before intervention, 6 months & 12months after intervention. Method of measurement: Change of WOMAC questionnaire scores. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactPegah Yavari
Physical Medicine and Rehabilitation Department, Shahid Beheshti University of Medical Sciences, Sch
Outcome results
None listed