Preterm labour. Preterm labour without delivery
Conditions
Interventions
Intervention 1: In Nifedipine group :
Patients were treated by 10 mg of nifedipine orally repeated up to 4 dozes per 20/min which was continued by 20mg/4-8hr and then every 12 hours till 48hr or 12hr
Treatment - Drugs
In Nifedipine group :
Patients were treated by 10 mg of nifedipine orally repeated up to 4 dozes per 20/min which was continued by 20mg/4-8hr and then every 12 hours till 48hr or 12hr after clinical
In Mg-sulfate group :
Patients were treated by 4gr/20min of Mg-Sulfate intravenously which continued by 1g/hr up to 24hr, in case of no contraindications treatment continued till 24hr or for 24hr af
Sponsors
urmia university of medical sciences, deputy of research and technology.
Eligibility
Sex/Gender
Female
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: Inclusion: Patients in 27th-36th of Gestation; 4 contractions per 20 min; dilatation of cervices > 1cm; effacement > 85 % ; intact membranes; have gestational age determined by LMP or ultrasonogeraphical study; Not to be included if : any indication for termination of pregnancy; any previous medication as tocolysis ; Placental abruption; infection; contra indictions of ca-blocker usage; primarily, a blood pressure below 90/50; Exclusion : were rupture of membranes; vaginal bleeding; fetal distress; dilatation of cervix >3cm; blood pressure below 90/50 mm Hg.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hampering contractions of labor. Timepoint: 48 hours from beginning of treatments. Method of measurement: observation by gynecologist. | — |
Secondary
| Measure | Time frame |
|---|---|
| Maternal complications : headache, hypotension, dyspnea and tachycardia. Timepoint: 48 hours of medication. Method of measurement: observation and physical examination by gynecologist.;Neonatal outcome : 1st min Apgar score. Timepoint: Just exact after labor. Method of measurement: Physical examination & observation by gynecologist. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Fariba nanbakhsh
Urumia University of Medical Science
Outcome results
None listed