Effect of vitamin D supplementation on diabetic patients

Assessment the effect of Vitamin D supplementation on insulin resistance and Adiponectin levels in patients with Diabetes Mellitus type 2

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

IRCT

Registry ID

IRCT2013052111421N2

Enrollment

Registered

2013-06-12

Start date

2013-02-01

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Type 2 diabetes. Non-insulin-dependent diabetes mellitus

Interventions

Intervention 1: Intervention supplement of 50000IU vitamin d3 per week for 8weeks. Intervention 2: control:edible parafin oil as pelacebo weekly for 8weeks.

Treatment - Drugs

Intervention supplement of 50000IU vitamin d3 per week for 8weeks

control:edible parafin oil as pelacebo weekly for 8weeks

Eligibility

Sex/Gender

All

Age

31 Years to 65 Years

Inclusion criteria

Inclusion criteria: Inclusion Criteria: - personal tendency to take part in the study - DM II which has been diagnosed at least one year ago or before - The onset of diabetes should be at age 30 or older. - BMI between 25 to 30 Kg/ M2 - Age: 31 to 65 years old - 25(OH) VitD serum levels between 10-30 ng/ml - Hb A1c < 8% - no history of smoking - no history of alcohol - no history of treatment with insulin - no monopose/ no pregnancy - no history of using agents interacting vit D like: corticosteroids, anti-epileptics and OCP in last 6 month - no history of using supplementary calcium and VitD in last 6 month - no history of angina pectoris, MI & CVA in last 12 months - no history of liver and kidney disease, chronic inflammatory diseases or thyroid diseases. - no history of treatment with thiasolidindions -failing to use prescribed supplemetary agent on the regular program -any change in diet during the study -any change in dose and type of prescribed medication during study -lack of tendency to complete the study -any history of sckeletal pain and fracture

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Adiponectin. Timepoint: before and after intervention. Method of measurement: kit.;Insulin resistance. Timepoint: before and after intervention. Method of measurement: Calculation.	—

Secondary

Measure	Time frame
BMI. Timepoint: before and after intervention. Method of measurement: Calculation based on weigh and height.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Kurosh Djafarian

Tehran University of Medical Sciences

kdjafarian@tums.ac.ir00

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026