Effect of vitamin E in the treatment of UTI in children

Effect of vitamin E supplementation in the treatment of UTI in children

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT201305199766N2

Enrollment

152

Registered

2013-06-12

Start date

2012-12-20

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Urinary Tract Infection. Urinary tract infection, site not specified

Interventions

Intervention 1: control : 50-75 mg/kg/day of IV ceftriaxone for inpatients and cefixime syrup 8mg/kg/day for outpatients for overall time of 14 days. Intervention 2: case :50-75 mg/kg/day of IV ceftr

Treatment - Drugs

control : 50-75 mg/kg/day of IV ceftriaxone for inpatients and cefixime syrup 8mg/kg/day for outpatients for overall time of 14 days

case :50-75 mg/kg/day of IV ceftriaxone for inpatients and cefixime syrup 8mg/kg/day for outpatients for overall time of 14 days + 100 units Vitamin E for 14 days

Eligibility

Sex/Gender

Female

Age

3 Years to 12 Years

Inclusion criteria

Inclusion criteria: Inclusion criterion: the diagnosis of urinary tract infection. Exclusion criteria: genito urinary anomalies; sacrum anomalies; baseline scar on kidneys; disrupted VCUG; persistent bacteriuaria; history of recurrent UTI's; bad compliance to therapy; positive cultures with more than one organism and renal calculi.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Time of fever cessation. Timepoint: day. Method of measurement: counting the days till there is no fever present.;Time of dysuria cessation. Timepoint: day. Method of measurement: counting the days till there is no dysuria present.;Time of frequency cessation. Timepoint: day. Method of measurement: counting the days till there is no frequency present.;Time of urgency cessation. Timepoint: day. Method of measurement: counting the days till there is no urgency present.;Time of dribbling cessation. Timepoint: day. Method of measurement: counting the days till there is no dribbling present.;Time of incontinence cessation. Timepoint: day. Method of measurement: counting the days till there is no incontinence present.;Time of abdominal pain cessation. Timepoint: day. Method of measurement: counting the days till there is no abdominal pain present.	—

Measure

Time frame

Time of fever cessation. Timepoint: day. Method of measurement: counting the days till there is no fever present.;Time of dysuria cessation. Timepoint: day. Method of measurement: counting the days till there is no dysuria present.;Time of frequency cessation. Timepoint: day. Method of measurement: counting the days till there is no frequency present.;Time of urgency cessation. Timepoint: day. Method of measurement: counting the days till there is no urgency present.;Time of dribbling cessation. Timepoint: day. Method of measurement: counting the days till there is no dribbling present.;Time of incontinence cessation. Timepoint: day. Method of measurement: counting the days till there is no incontinence present.;Time of abdominal pain cessation. Timepoint: day. Method of measurement: counting the days till there is no abdominal pain present.

—

Secondary

Measure	Time frame
Urine culture. Timepoint: 48 h after the start of treatment and 7-10 days post treatment. Method of measurement: it is positive if there are more than 100000 CFU.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Sara Rasti

Arak University of Medical Sciences

rasti@arakmu.ac.ir+98 86 1417 3645

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026