obesity. Obesity due to excess calories
Conditions
Interventions
Intervention 1: whole-grain group:The individual energy requirements will be calculated based on recommendations of the Institute of medicine. The target macro nutrient composition for all participant
Treatment - Other
whole-grain group:The individual energy requirements will be calculated based on recommendations of the Institute of medicine. The target macro nutrient composition for all participants will be 53% of
Recommendation group: information about healthy diet has been prescribed for this group.Subjects in the non intervention group also were given a list of whole grain foods and will be asked not to cons
Sponsors
Vice Chancellor for Research, Isfahan University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
8 Years to 15 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: female; aged 8-15 years; body mass index greater than 85th percentile for age and sex; lack of adherence to a specific diet and the use of medications and supplements and no history of chronic diseases. Exclusion criteria: history of chronic diseases; the use of medications and supplements such as multivitamin mineral supplementation, omega-3 fatty acids, Aspirin, etc in the past 6 months, hormone therapy and alterations in physical activity
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Serum high sensitive-C Reactive Protein (hs-CRP) levels. Timepoint: Week 2, Week 8, Week 12, Week 18. Method of measurement: high sensitive immunoturbidimetry, mg/dL.;Serum Amyloid A (SAA) levels. Timepoint: Week 2, Week 8, Week 12, Week 18. Method of measurement: Enzyme-Linked Immunosorbent Assay (ELISA) ?mg/dL.;Serum Inter-Cellular Adhesion Molecule 1 (sICAM-1) levels. Timepoint: Week 2, Week 8, Week 12, Week 18. Method of measurement: Enzyme-Linked Immunosorbent Assay (ELISA) ?µg/L.;Serum vascular cell adhesion molecule 1 (sVCAM-1) levels. Timepoint: Week 2, Week 8, Week 12, Week 18. Method of measurement: Enzyme-Linked Immunosorbent Assay (ELISA) ?µg/L.;Serum leptin levels. Timepoint: Week 2, Week 8, Week 12, Week 18. Method of measurement: Enzyme-Linked Immunosorbent Assay (ELISA) ?ng/mL. | — |
Secondary
| Measure | Time frame |
|---|---|
| Weight. Timepoint: Baseline, Week 2, Week 8, Week 12, Week 18. Method of measurement: scale, kilogram.;Waist circumference. Timepoint: Baseline, Week 2, Week 8, Week 12, Week 18. Method of measurement: meter, centimeter.;Hip circumference. Timepoint: Baseline, Week 2, Week 8, Week 12, Week 18. Method of measurement: meter, centimeter.;Body mass index. Timepoint: Baseline, Week 2, Week 8, Week 12, Week 18. Method of measurement: kg/m2, Weight/Height square.;Systolic blood pressure. Timepoint: Baseline, Week 2, Week 8, Week 12, Week 18. Method of measurement: mmHg, digital sphygmomanometer.;Diastolic blood pressure. Timepoint: Baseline, Week 2, Week 8, Week 12, Week 18. Method of measurement: mmHg, digital sphygmomanometer.;Fasting blood sugar. Timepoint: Week 2, Week 8, Week 12, Week 18. Method of measurement: mg/dL, Colorimetric.;Serum Triglyceride levels. Timepoint: Week 2, Week 8, Week 12, Week 18. Method of measurement: photometrics, mg/dL.;Serum total cholesterol levels. Timepoint: Week 2, Week 8, Week 12, Week 18. Method of measurement: photometrics, mg/dL.;Serum Low-Density Lipoprotein cholesterol (LDL-c) levels. Timepoint: Week 2, Week 8, Week 12, Week 18. Method of measurement: Enzymatic, mg/dL.;Serum High-Density Lipoprotein cholesterol (HDL-c) levels. Timepoint: Week 2, Week 8, Week 12, Week 18. Method of measurement: photometrics, mg/dL. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAhmad Esmaillzadeh
Department of Community Nutrition, School of Nutrition and Food Science, Isfahan University of Medic
Outcome results
None listed