Gonarthrosis [arthrosis of knee]. Primary gonarthrosis, bilateral
Conditions
Interventions
Intervention 1: Intervention group: For the HA group, 2.5 mL of hyaluronic acid is injected intraarticulary via the inferomedial of patella. Intervention 2: Intervention group: The HD group, is receiv
Sponsors
Shahid Beheshti University of Medical Sciences
Eligibility
Sex/Gender
All
Age
50 Years to 75 Years
Inclusion criteria
Inclusion criteria: Patients with chronic osteoarthritis Grade 2 or higher of OA in radiology Age over 50 years Morning stiffness less than 30 minutes 3 month unresponsiveness to conservative therapy
Exclusion criteria
Exclusion criteria: Severe underlying diseases like diabetes and/or hypothyroidism, immune suppression or deficiency Serious local infectious or inflammatory knee disease Anticoagulant drug history during three last months History of corticosteroid therapy in past year History of prolotherapy in past year History of intraarticular injection in past year Indication for surgical arthroplasty
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain. Timepoint: 3 months. Method of measurement: VAS.;WOMAC Index. Timepoint: 3 months. Method of measurement: The Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC). | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMehrdad Taheri
Shahid Beheshti University of Medical Sciences
Outcome results
None listed