Effect of fluid therapy in reducing complications of spinal anesthesia

Comparison effect of intravascular administration of colloid versus crystalloid in prevention of hypotension after spinal anesthesia for cesarean section

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT2013051612094N2

Enrollment

100

Registered

2013-06-29

Start date

2012-11-21

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Spinal anesthesia. Other complications of spinal and epidural anaesthesia during pregnancy

Interventions

Intervention 1: Intervention group1 : Colloid infusion, 20 minutes before spinal anesthesia. Intervention 2: Intervention group 2 : colloid infusion with spinal anesthesia. Intervention 3: Control

Prevention

Intervention group1 : Colloid infusion, 20 minutes before spinal anesthesia

Intervention group 2 : colloid infusion with spinal anesthesia

Control group1 : crystalloid infusion, 20 min before spinal anesthesia

control group 2 : crystalloid infusion with spinal anesthesia

Eligibility

Sex/Gender

All

Age

18 Years to 40 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Candidates for elective cesarean surgery; ASA I-II; 18-40 years old. Exclusion criteria: Patients who received intravenous fluids before entering the operating room; BMI=30; ASA>3; Age less than 18 years and more than 40 years; Contraindications to spinal anesthesia procedures; Emergency cesarean section; Amount of intraoperative bleeding over 1000cc; History of hypertension and blood pressure in pregnancy; Instances may increase the risk of bleeding and inertia.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Blood pressure changes. Timepoint: Befor spinal, every 3 minutes to initial 10 minutes, and then every 5 minutes until recovery. Method of measurement: Perioperative monitoring.;Heart rate changes. Timepoint: Befor spinal, every 3 minutes to initial 10 minutes, and then every 5 minutes until recovery. Method of measurement: Perioperative monitoring.	—

Secondary

Measure	Time frame
Nausea & Vomiting. Timepoint: Postoperative time. Method of measurement: Clinical observation.;Chest discomfort. Timepoint: Duration of Surgery. Method of measurement: Recorded in the questionnaire.;Neonate apgar. Timepoint: Duration of Surgery. Method of measurement: Recorded in the questionnaire.;Efedrin require. Timepoint: Duration of Surgery. Method of measurement: Recorded in the questionnaire.	—

Measure

Time frame

Nausea & Vomiting. Timepoint: Postoperative time. Method of measurement: Clinical observation.;Chest discomfort. Timepoint: Duration of Surgery. Method of measurement: Recorded in the questionnaire.;Neonate apgar. Timepoint: Duration of Surgery. Method of measurement: Recorded in the questionnaire.;Efedrin require. Timepoint: Duration of Surgery. Method of measurement: Recorded in the questionnaire.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMajid Razavi

Mashhad University of Medical Sciences

Razavim@mums.ac.ir+98 51 1852 5029

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026