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Comparison of One-Stage Full-Mouth Disinfection and Quadrant-Wise Scaling and Root Planing

Comparison of the effects of one-stage full-mouth disinfection and quadrant-wise scaling and aoot planing on serum levels of IL-27 and clinical parameters following treatment of moderate-to-severe chronic periodontitis

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2013051313312N1
Enrollment
40
Registered
2013-08-04
Start date
2012-08-05
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

chronic periodontits. chronic periodontits

Interventions

Intervention 1: After blood samples were taken in the test group , the entire oral cavity was cleaned by an ultrasonic scaler in two sessions in less than 24 hours in order to decrease pathogenic orga
an antiseptic mouthwash (0.2% chlorhexidine) was used to reduce bacterial load in the saliva and on the tonsils. Intervention 2: The control group patients underwent scaling and root planing procedure
Treatment - Other
After blood samples were taken in the test group , the entire oral cavity was cleaned by an ultrasonic scaler in two sessions in less than 24 hours in order to decrease pathogenic organisms’ counts. S
an antiseptic mouthwash (0.2% chlorhexidine) was used to reduce bacterial load in the saliva and on the tonsils.
The control group patients underwent scaling and root planing procedures at two-week intervals for each quadrant after blood samples were taken.

Sponsors

Vice chancellor for research, Tabriz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
25 Years to 70 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria:The subjects had at least 12 teeth (irrespective of third molars and teeth with orthodontic appliances, bridgeworks, crowns and implants) with the 30% of the teeth with clinical attachment loss of =3 mm? radiographic evidence of bone loss in each group. Exclusion criteria: included systemic conditions? conditions which delay would healin? a history of radiotherapy or immune-suppressive treatment modalities? pregnancy or breast-feeling? use of systemic antibiotics during the two previous months? a history of continuous consumption of NSATDs ? a history of scaling and root planing during the previous year

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Serum levels of IL_27. Timepoint: befor intervation,2 month and 4 month after intervation. Method of measurement: special laboratory kit.

Secondary

MeasureTime frame
Bleeding on probing. Timepoint: befor intervation,2 month and 4 month after intervation. Method of measurement: probing.;Clinical attachment level. Timepoint: befor intervation,2 month and 4 month after intervation. Method of measurement: distance between floor of pocket to CEJ.;Probing depth. Timepoint: befor intervation,2 month and 4 month after intervation. Method of measurement: distance between floor of the pocket to free gingiva.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAmirreza Babaloo

Tabriz University of Medical Sciences

amirezababaloo@yahoo.com+98 914 311 6842

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026