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Cimetidine in the treatment of primary dysmenorrhea

Comparison of the analgesic effect of cimetidine versus mefnamic acid,placebo in primary dysmenorrhea in girl student in semnan town in 2012.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2013051212701N2
Enrollment
90
Registered
2013-06-12
Start date
2013-05-22
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Primary dysmenorrhoea. Primary dysmenorrhoea

Interventions

Intervention 1: Group B mefenamic acid capsules of 250 mg every 6 hours for 4 days of menstruation is given. Intervention 2: Group C placebo capsules for 4 days is menstruation. Intervention 3: A grou
Treatment - Drugs
Group B mefenamic acid capsules of 250 mg every 6 hours for 4 days of menstruation is given.
Group C placebo capsules for 4 days is menstruation.
A group of cimetidine 300 mg every 6 hours for 4 days of menstruation is given.

Sponsors

Semnan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 22 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: age 22-18 years old; one year of regular menstrual cycle; the first three days of menstruation; menstrual complaints of pain; pain cycle so that more medication may be needed. Exclusion criteria: lack of sufficient cooperation; BMI more than 26; history of gastrointestinal disease, such as I BS; urological disease (repetition burning urination); Endometriosis; Epilepsy; genital system disorders such as infectious disease; previous abdominal surgery; a history full term pregnancy; - a history of sensitivity to cimetidine; drugs interaction with cimetidine for example: Warfarin - phenytoin - Inderal - nifedipine. Diazepam and antidepressants - Lidocaine - theophylline - metronidazole; use of other drugs to reduce the pain of dysmenorrhea.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Analgesia. Timepoint: For 6 months after intervention. Method of measurement: Numeric Rating Pain Scale.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactForozeshfard Mohammad

Semnan University of Medical Sciences

mff@sem-ums.ac.ir+98 23 1444 1021

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026