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Comparing the analgesic effect of extra virgin olive oil and ibuprofen for primary dysmenorrhea

Comparing the analgesic effect of extra virgin olive oil and ibuprofen for primary dysmenorrhea in students residing in dormitories of Borujerd islamic azad university: A randomized, Cross-Over clinical trial

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT2013051110804N2
Enrollment
60
Registered
2013-07-23
Start date
2009-10-23
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

dysmenorrhea. dysmenorrhea

Interventions

Intervention 1: First treatment/ control group:taking daily 25 cc of extra virgin olive oil for 2 months, Then ibuprofen 400 mg, three times a day for 2 cycles during the 3 first days of menstruation.
Treatment - Drugs
First treatment/ control group:taking daily 25 cc of extra virgin olive oil for 2 months, Then ibuprofen 400 mg, three times a day for 2 cycles during the 3 first days of menstruation.
The second treatment/ control group: taking ibuprofen 400 mg three times a day during first 3 days of menstruation, Then, taking daily 25 cc of extra virgin olive oil, for 2 menstrual cycles.

Sponsors

Vice chancellor for research, Islamic azad university, Borujerd branch
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
17 Years to 30 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Not being married, 17 to 30 years old; living in Islamic Azad university Borujerd branch dormitory; having score 4 to 10 for dysmenorrhea according to pain scale; having regular menstrual periods between 21 to 35 days, no history of myoma, pelvic tumor, endometriosis and pelvic inflammatory disease; no taking oral particular drug, no history of allergy to herbal drugs. Exclusion criteria: allergy to olive oil or non-steroidal anti inflammatory drugs;taking inappropriate dosage and forgetting the time table.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Severity of primary dysmenorrhea. Timepoint: 4 menstrual cycles, one cycle before the study and 2 cycles during the study after using extra virgine oil and 2 cycles after taking ibuprofen. Method of measurement: visual analogue scale.

Secondary

MeasureTime frame
Nausea. Timepoint: Before and after the treatment. Method of measurement: Questionnaire.;Diarrhea. Timepoint: Before and after the treatment. Method of measurement: Questionnaire.

Countries

Iran (Islamic Republic of)

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026