Spinal Cord Injury. Injury Of Spinal Cord, Level Unspecified
Conditions
Interventions
Intervention 1: In intervention group, at first bone marrow aspiration (10ml) will be done and mesenchymal stem cells will be collected using centrifuge and Ficoll solvent. Cells will be cultured and
Treatment - Surgery
Treatment - Drugs
In intervention group, at first bone marrow aspiration (10ml) will be done and mesenchymal stem cells will be collected using centrifuge and Ficoll solvent. Cells will be cultured and after proliferat
In control group just vehicle of cells (distilled water) with the same volume of intervention group (5ml) will be injected to the sub arachnoid space of patients. Injecting solvent will be injected sl
Sponsors
Shahid Sadoughi Yazd University Of Medical Sciences, Vice Chancellor for Research
Eligibility
Sex/Gender
All
Age
13 Years to 60 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: filling the questionnaire by patient and his/her family; age 13-60; no more than 3 months passed from injury date, no history of cancer in patient and his family; no history to other chronic disorder; no other acute disease at present; self control on breathing; no contribution in the other studies; no convulsion and fever; no infectious diseases in patient like AIDS and hepatitis, and meningitis. Exclusion criteria: patient request; occurrence of fever and convulsion after cell therapy, occurrence of any other complication; infection, instability of patient's health conditions ; worsening of the patient's disease.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Evaluation of Generation of Ectopic Tissue Such as Tumor After Stem Cell Therapy. Timepoint: Three months after third injection. Method of measurement: MRI; Physical Examination; Biochemical Tests About Presence of Ectopic Tissue or Tumor in Patients. | — |
Secondary
| Measure | Time frame |
|---|---|
| Improvement In Somatic Sensation And Control Of Bladder , And Motor Function Improvements. Timepoint: 1 Month. Method of measurement: Physical Examination. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactHamid Hobobati
Shahid Sadoughi Yazd University Of Medical Sciences, Yazd, Iran
Outcome results
None listed