Chronic periodontitis. Chronic periodontitis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Inclusin criteria: patients with severe periodontitis? patients with moderate periodontitis? patients with gingivitis? subjects with periodontal healthy. Exclusion criteria: periodontal treatment or antibiotic therapy within the last 3 months? presence of any systemic disease (e.g.,diabetes mellitus, asthma)? working in night shifts? xerostomia or any other disease of the salivary glands? less than 20 teeth? intake of any drug known to alter melatonin levels (e.g., for sleeping disorders) or to be immunosuppressive? usage of partial or total prosthesis? pregnancy? lactation? acute infection? immunodeficiency? history of radio- or chemotherapy? and any conditions necessitating antibiotic premedication for dental appointment.
Exclusion criteria
Exclusion criteria:
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| Severity of disease. Timepoint: After intervention. Method of measurement: Pocket depth. | — |
Primary
| Measure | Time frame |
|---|---|
| Melatonin. Timepoint: Before intervention. Method of measurement: Concentration. | — |
Countries
Iran (Islamic Republic of)
Contacts
Ahvaz University of Medical Sciences