Skip to content

Treatment of bronchiolitis

Evaluation of efficacy of combination of nebulized salbutamol with different concentration of saline ( normal saline 0/9%, hypertonic saline 3%, hypertonic saline 5%) in bronchiolitis

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT2013050213207N1
Enrollment
180
Registered
2013-08-26
Start date
2012-10-14
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bronchiolitis. Other acute lower respiratory infections

Interventions

Intervention 1: Infants who have inclusion criteria and their respiratory rate is between 30 - 60 per minute devide in 3 groups. First group receive 5 ml normal saline 0/9 % and 0/15 mg/kg nebulized s
Treatment - Drugs
Third group receive 5 ml hypertonic saline 5% and 0/15 mg/kg nebulized salbutamol.
Infants who have inclusion criteria and their respiratory rate is between 30 - 60 per minute devide in 3 groups. First group receive 5 ml normal saline 0/9 % and 0/15 mg/kg nebulized salbutamol
Second group receive 5 ml hypertonic saline 3 % and 0/15 mg/kg nebulized salbutamol.

Sponsors

Vice.chancellor for research of Zahedan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
No minimum to 2 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: age less than 2 year old; history of recent upper respiratory viral infection which caused wheez and crakle in ascultation; CBSS 4-8 in admit. Exclusion criteria: age less than 1 month or more than 2 years old; history of recurrent attack of wheez; sever neurologic disorder; consolidation in Chest x ray; immune deficiency; congenital heart disease; history of prematurity(gestational age less than 34 weeks); birth weight less than 2500 gr; sturation of oxygen less than 85% in room; CBSS less than 4 or more than 8; unstable hemodynamic(heart rate more than 200 per minute,blood pressure 2 standard deviation more or less than normal range for age and sex ,respiratory rate more than 70 per minute).

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
O2 saturation. Timepoint: Pretreatment and each 20 minute up to 3 times after the begining of the treatment. Method of measurement: With pulse oximetery.;Respiratory rate. Timepoint: Pretreatment and each 20 minute up to 3 times after the begining of treatment. Method of measurement: Counting of respiratory rate in 1 minute.;Heart rate. Timepoint: Pretreatment and each 20 minute up to 3 times after the begining of teratment. Method of measurement: Counting of the heart rate in 1 minute.;Intercostal retraction. Timepoint: Pretreatment and each 20 minute up to 3 times after the begining of the treatment. Method of measurement: Physical exam and score of CBSS (0,1,2,3).;Dyspnea. Timepoint: Pretreatment and each 20 minute up to 3 times after the begining of the treatment. Method of measurement: Physical examine and score of CBSS(0,1,2,3).;Wheeze. Timepoint: Pretreatment and each 20 minute up to 3 times after the begining of the treatment. Method of measurement: Physical exam and score of the CBSS(0,1,2,3).

Secondary

MeasureTime frame
Duration of admission. Timepoint: From admossion up to discharge from hospital. Method of measurement: Counting of the dyes of admission.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMaryam Baktash

Zahedan University of Medical Sciences

Maryam_baktash80@yahoo.com+98 54 1342 5593

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026