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Effect of continues positive airway pressure on de-airing process.

Comparative evaluation of the effects of continuous positive airway pressure and zero airway pressure during cardiopulmonary bypass on cardiac de-airing after open heart surgery in patients with rheumatic heart valves diseases.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2013043013181N1
Enrollment
40
Registered
2013-09-11
Start date
2012-03-19
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cardiac chamber de-airing. Chronic rheumatic heart diseases

Interventions

Intervention 1: After turning the ventilator off, the flow of oxygen flow was maintained at the rate of 0.5L/min and the APL valve was placed in “Man” position on 20 mbar (20 hectopascal, 15mmHg). Int
Prevention
After turning the ventilator off, the flow of oxygen flow was maintained at the rate of 0.5L/min and the APL valve was placed in “Man” position on 20 mbar (20 hectopascal, 15mmHg).
During the surgery and CPB, the ventilator (Drager, Fabius) was turned off and the flow of fresh air was totally ceased and adjustable pressure limit (APL) valve was placed in “Spont” position.

Sponsors

Isfahan university of medical science
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 80 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Patients candidate for aorta and/or mitral valve with/without tricuspid valve replacement surgery; Ejection fraction >40%; Patients without heart surgery; absence of history of dysphasia, odinophagia and previous oesophageal surgery. Exclusion criteria: Intra aortic balloon while weaning from CPB.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Time of de-airing. Timepoint: from mechanical ventilation bigining untill end of de-airing process. Method of measurement: minute.;Amount of air bubble in left atrium cavity durig de-airing. Timepoint: from mechanical ventilation bigining untill end of de-airing process. Method of measurement: scale: mild, moderate, sever.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMijtaba Mansouri

Isfahan Medical School

mansouri@med.mui.ac.ir+98 31 1775 0252

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026