Condition 1: Dyspepsia. Condition 2: periodontitis. Indigestion Chronic periodontitis
Conditions
Interventions
Intervention 1: Intervention group: Periodontal pocket reduction therapy by first non surgical and then surgical therapy (different types of flap surgery) after about a month+ 500mg Amoxicillin and 25
Treatment - Surgery
Treatment - Drugs
Intervention group: Periodontal pocket reduction therapy by first non surgical and then surgical therapy (different types of flap surgery) after about a month+ 500mg Amoxicillin and 250mg Metronidazol
Control group: 500mg Amoxicillin and 250mg Metronidazole three times a day for two weeks
Sponsors
Vice chancellor for research and technology, Shahid Sadoughi Yazd University of Medical Sciences
Eligibility
Sex/Gender
All
Age
20 Years to 60 Years
Inclusion criteria
Inclusion criteria: Patients older than 20 years who are referred to the department of Gastroenterology of Shahid Sadoughi hospital for dyspeptic symptoms, periodontal disease is diagnosed in them and the presence of Helicobacter Pylori is confirmed in gastrointestinal tract and sub gingival plaque sample. Exclusion criteria includes: 1- Taking local or systemic antimicrobial agents, Proton Pump Inhibitors, H2-blockers and Bismuth from one month before the study. 2- History of upper gastrointestinal tract bleeding or abdominal cancer. 3- Presence of systemic conditions such as Diabetes Mellitus. 4- Smoking. 5- Undergoing periodontal treatment in the past 6 months. 6- Pregnancy. 7- Being older than 60 years.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Recurrence of Dyspepsia emanating from Helicobacter Pylori. Timepoint: 2, 4 and 6 months after completion of antibiotic therapy. Method of measurement: Asking the patients on the phone. | — |
Countries
Iran (Islamic Republic of)
Outcome results
None listed