IHD. Acute transmural myocardial infarction - Acute subendocardial myocardial infarction
Conditions
Interventions
Intervention 1: Intervention group:in the intervention group, Medonex is diluted in saline with a concentration of 0.1 µg/kg/ml. Start with an infusion pump: within 10 minutes as a loading dose (1 µg/
Sponsors
Mashhad University of Medical Sciences
Eligibility
Sex/Gender
All
Age
35 Years to 75 Years
Inclusion criteria
Inclusion criteria: Patients aged 35 to 75 referring to eduacational medical hospital ASA class II Candidates for coronary bypass surgery with an elective cardiopulmonary pump,
Exclusion criteria
Exclusion criteria: Emergency operation Simultaneous heart valve operation Underlying lung or liver or kidney, thyroid or gastrointestinal disease (nausea-vomiting-diarrhea) History of previous heart surgery Fever Trauma Carotid artery occlusion Diabetes Difficult and longer intubation than 20 seconds BMI more than 30 kg/m2 Patient with heart rate less than 50 per minute History of heart bundle block History of treatment with clonidine and methyldopa Ejection fraction less than 35%
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mean arterial pressure and heart rate and hemodinamic parameters in the attached tables at the end of the proposal. On entering the operating room, basic and hemodinamic information (T1) was recorded and at the time, 15 minutes after tracheal intobation (T2) and at the time, 15 minutes after From the sternotomy (T3) and 15 minutes after the start of the cardiopulmonary bypass pump (T4) and 30 minutes after disconnecting from the cardiopulmonary bypass pump (T5) by the anesthesia assistant, the dose is recorded in the checklist. Total propofol, sufentanil, fentanyl, epinephrine, dobutamine, nitroglycerin, norepinephrine, and atropine are recorded in the checklist at the end of the procedure. Timepoint: Mean arterial pressure and heart rate and hemodynamic parameters in the attached tables at the end of the proposal. On entering the operating room, basic and hemodynamic information (T1) was recorded and at the time, 15 minutes after tracheal intubation (T2) and at the time, 15 minutes after From the sternotomy (T3) and 15 minutes after the start of the cardiopulmonary bypass pump (T4) and 30 minutes after disconnecting from the cardiopulmonary bypass pump (T5) by the anesthesia assistant, the dose is recorded in the checklist. Total propofol, sufentanil, fentanyl, epinephrine, dobutamine, nitroglycerin, norepinephrine, and atropine are recorded in the checklist at the end of the procedure. Method of measurement: Checklist for measuring vital signs from monitoring USCOM. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactShima Sheybani
Mashhad University of Medical Sciences
Outcome results
None listed