Obsessive Compulsive Disorder. Obsessive-compulsive disorder
Conditions
Interventions
Intervention 1: ACT was based on an ACT manual for OCD developed by Twohig (10). A Ph.D. clinical psychologist (first author) under the supervision of an experienced clinical psychologist in treating
The "Man in the hole" metaphor was used to illustrate how the patient's efforts to regulate obsessions are ineffective (session 2)
The " Tow scales " metaphor was used to illustrate the possible benefits of acceptance of obsessions and anxiety rather than attempting to control or reduce them ( sessions 3 and 4 )
using defusion, contact with the present or mindfulness, and self as context exercises ( sessions 5 and 6 )
recognize his values
and preventing relapse ( sessions 7 and 8 ). Intervention 2: The patients in drug group received a different SSRI (sertraline=50-200 mg/d
fluoxetine=20-80 mg/d) for 10 weeks, which was monitored by two psychiatrist. Intervention 3: The combination group received both ACT and a different SSRI (sertraline=50-200 mg/d
fluoxetine=20-80 mg/d) for 10 weeks.
Behavior
Treatment - Drugs
ACT was based on an ACT manual for OCD developed by Twohig (10). A Ph.D. clinical psychologist (first author) under the supervision of an experienced clinical psychologist in treating OCD provided ACT
and preventing relapse ( sessions 7 and 8 ).
The patients in drug group received a different SSRI (sertraline=50-200 mg/d
fluoxetine=20-80 mg/d) for 10 weeks, which was monitored by two psychiatrist.
The combination group received both ACT and a different SSRI (sertraline=50-200 mg/d
Sponsors
Tehran University of Medical Science
Eligibility
Sex/Gender
All
Age
18 Years to 50 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria : a primary diagnosis of OCD according to DSM-IV-TR ; age between 18 to 50 years; OCD symptoms duration of at least 1year; Exclusion criteria: having a current or past psychotic disorder ; suicidal tendencies; medical illness ; substance abuse disorder ; personality disorder; had been treated with either pharmacotherapy or psychotherapy in the 1month preceding baseline;patients with other axis I disorders (except anxiety disorders and major depression disorder and dysthymia disorder) and axis II disorders
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Obsessive - compulsive symptoms. Timepoint: pre-middle and post-treatment. Method of measurement: The Yale-Brown Obsessive-Compulsive Scale (Y-BOCS). | — |
Secondary
| Measure | Time frame |
|---|---|
| Depression. Timepoint: pre-middle and post treatment(tenth week). Method of measurement: Beck Depression Inventory-II-Second Edition (BDI-II).;Anxiety. Timepoint: pre-middle and post treatment(tenth week). Method of measurement: Beck Anxiety Inventory (BAI).;Experiential avoidance. Timepoint: pre-middle and post treatment(tenth week). Method of measurement: Acceptance and Action Questionnaire (AAQ).;Quality of Life. Timepoint: pre-and post treatment(tenth week). Method of measurement: World Health Organization Quality of Life-BREF (WHOQOL-BREF). | — |
Countries
Iran (Islamic Republic of)
Contacts
Public Contactyaghoob vakili
Tehran psychiatric institute
Outcome results
None listed