Comparing Pain & Swelling after Surgical Extraction of Mandibular Third Molar in Intra-oral Dexamethasone Injection and without it

Comparing Pain and Swelling after Surgical Extraction of Mandibular Third Molar in Dexamethasone Injection to Medial Pterygoid and without Corticosteroid Method

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2013042713140N1

Enrollment

Registered

2013-05-19

Start date

2013-04-28

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Oral health. Factors influencing health status and contact with health services

Interventions

Intervention 1: For the case group, after the inferior alveolar block injection and before starting the surgery, single dose of dexamethasone (8mg) will injected into medial pterygoid and pterygomandi

Treatment - Drugs

For the case group, after the inferior alveolar block injection and before starting the surgery, single dose of dexamethasone (8mg) will injected into medial pterygoid and pterygomandibular space

For the control group after inferior alveolar block injection, the surgical removal of impacted third mandibular molar will done using no corticosteroid

Eligibility

Sex/Gender

All

Age

18 Years to 35 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: non pregnant participants have single impacted mandibular third molar in healthy and without pericoronitis manner. They must have no contra-indication for injection of the corticosteroid and lidocaine with epinephrine and also, should not medicated by any possibly bias maker drug. Type of the impaction, must not provide sever difficulty. The participants should be mentally at healthy level and provide written informed consent to incorporate in the study. Exclusion criteria: unwilling participants to continue the study and those with abnormality of wound healing process.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Pain. Timepoint: 48 hours and one week after intervention. Method of measurement: Visual analogue scale of pain- Number of reqiered analgesics tablets.;Swelling. Timepoint: 48 hours and one week after intervention. Method of measurement: Questionnaire.;Trismus. Timepoint: 48 hours and one week after intervention. Method of measurement: Maximum mouth-opening.;General patients' satisfaction. Timepoint: 48 hours and one week after intervention. Method of measurement: Visual analogue scale for satisfaction.;Quality of life. Timepoint: 96 hours and one week after intervention. Method of measurement: Questionnaire.	—

Measure

Time frame

Pain. Timepoint: 48 hours and one week after intervention. Method of measurement: Visual analogue scale of pain- Number of reqiered analgesics tablets.;Swelling. Timepoint: 48 hours and one week after intervention. Method of measurement: Questionnaire.;Trismus. Timepoint: 48 hours and one week after intervention. Method of measurement: Maximum mouth-opening.;General patients' satisfaction. Timepoint: 48 hours and one week after intervention. Method of measurement: Visual analogue scale for satisfaction.;Quality of life. Timepoint: 96 hours and one week after intervention. Method of measurement: Questionnaire.

—

Secondary

Measure	Time frame
Trismus. Timepoint: During the study. Method of measurement: Maximum mouth opening- Patienits complaint.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactShiarani Mohammadjavad

Faculty of Dentistry, Isfahan University of Medical Sciences

javaad.sh_f@yahoo.com+98 38 2422 5600

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026