The effects of ciprofloxacin on the treatment of bacterial otitis media

Comparison of therapeutic effect of ciprofloxacin powder and drops in the chronic bacterial otitis media

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20130427013136N7

Enrollment

Registered

2020-03-11

Start date

2018-09-23

Completion date

Unknown

Last updated

2020-03-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic bacterial otitis media. Chronic mucoid otitis media

Interventions

Intervention 1: Intervention group: After suction, 30 mg ciprofloxacin powder (Ronak pharmaceutical company, Kaveh industrial town, Iran) will use for once, by insufflation in to middle ear space and

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients with chronic bacterial otitis media

Exclusion criteria

Exclusion criteria: Suspected Patients to mixed bacterial and fungal otitis Suspected Patients to otomycosis patients with external otitis patients without rupture of the eardrum

Design outcomes

Primary

Measure	Time frame
Pain. Timepoint: Before intervention and 2 weeks after intervention. Method of measurement: Severity of pain will determined by the patient's expression or pain index (Visual Analog Scale-VAS) which are between 0-10.;Swelling. Timepoint: Before intervention and 2 weeks after intervention. Method of measurement: Severity of swelling will determine based on the examination of the ear by the physician.;Discharge. Timepoint: Before intervention and 2 weeks after intervention. Method of measurement: Severity of discharge will determine based on the examination of the ear by the physician.	—

Measure

Time frame

Pain. Timepoint: Before intervention and 2 weeks after intervention. Method of measurement: Severity of pain will determined by the patient's expression or pain index (Visual Analog Scale-VAS) which are between 0-10.;Swelling. Timepoint: Before intervention and 2 weeks after intervention. Method of measurement: Severity of swelling will determine based on the examination of the ear by the physician.;Discharge. Timepoint: Before intervention and 2 weeks after intervention. Method of measurement: Severity of discharge will determine based on the examination of the ear by the physician.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSaeid Mahdavi Omran

Babol University of Medical Sciences

s.mahdavi@mubabol.ac.ir+98 11 3219 9936

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026