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The effect of oral melatonin on the clinical feature in patients with ischemic stroke

The effect of oral melatonin on the clinical feature in patients with ischemic stroke: a randomized clinical trial

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20130424013110N7
Enrollment
60
Registered
2019-08-24
Start date
2019-08-23
Completion date
Unknown
Last updated
2019-10-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ischemic stroke. Cerebral infarction

Interventions

Intervention 1: Intervention group: Patients in the intervention group will receive 1 melatonin tablet (3 mg) every night from the beginning of the study to the time of discharge. Intervention 2: Cont

Sponsors

Arak University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Age 18 to 80 years old Patients satisfaction GCS 14-15 receiving narcotics and sedatives at least six hours previously Ischemic stroke

Exclusion criteria

Exclusion criteria: Recent use of CNS depressant drugs Impending death Unwillingness to cooperate

Design outcomes

Primary

MeasureTime frame
Sleep quality. Timepoint: Befor intervention and 1 month after start of intervention. Method of measurement: The Pittsburgh Sleep Quality Index.;Vital signs. Timepoint: Before intervention, then every 6 hours. Method of measurement: Blood pressure will measured by Sphygmomanometer, pulse and breathing by counting in a minute by a hand watch.;Volume of red blood cells. Timepoint: Before intervention, then every 48 hours. Method of measurement: in mili liter.;Score of NIHSS scale. Timepoint: Before intervention, time of discharge and one month after intervention. Method of measurement: NIHSS questionnaire (0-42) score.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr mehran fazel

Arak University of Medical Sciences

dr.a.jokar@gmail.com+98 86 3222 2003

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026