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Suppository indomethacin and combined indomethacin- acetaminophen for pain after cesarean section

Comparison of suppository indomethacin and combination of indomethacin- acetaminophen on post operative pain after cesarean section

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT2013042013069N1
Enrollment
76
Registered
2013-09-22
Start date
2013-03-06
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post-cesarean pain. Delivery by caesarean section, unspecified

Interventions

Intervention 1: Group A: A 50-mg indomethacin rectal suppository is administered immediately after a cesarean every 6 hours for 24 hours after the operation. Intervention 2: Group B: Two rectal suppos
Treatment - Drugs
Group A: A 50-mg indomethacin rectal suppository is administered immediately after a cesarean every 6 hours for 24 hours after the operation.
Group B: Two rectal suppositories (A 50-mg indomethacin and a 325-mg acetaminophen) are administered immediately after cesarean every 6 hours for 24 hours after the operation.

Sponsors

Kermanshah University of Medical Sciences, Vice chancellor for research
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 45 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria include elective cesarean section with lower uterine segment incision; pregnancy over 37 weeks. Exclusion criteria include anemia, multiple pregnancies, poly hydramnious, prolonged labor, premature rupture of membranes, diabetes, high blood pressure, renal disease, history of drug abuse or smoking, cardiovascular diseases and coagulation disorders. or other underlying diseases.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Pain severity. Timepoint: 2, 4, 6, 12, 24 h after operation. Method of measurement: VAS with a 10-cm ruler is used and patient shows her pain on the ruler.

Secondary

MeasureTime frame
Nausea and vomiting, need for analgesic and anti-emetic. Timepoint: 2, 4, 6, 12, 24 h after operation. Method of measurement: Ask from patient by resident.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Mohammad Rasoul Ghadami

Kermanshah University of Medical Sciences

mrghadami@kums.ac.irmr_ghadami@yahoo.com+98 83 1427 6310

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026