orthodontic relapse. Fitting and adjustment of orthodontic device
Conditions
Interventions
Intervention 1: For control group: normal saline injection (1 .2 mg) in the sixth front teeth depth pocket, two weeks after bleaching. Intervention 2: For intervention group: simvastatin injection in
Treatment - Drugs
For control group: normal saline injection (1 .2 mg) in the sixth front teeth depth pocket, two weeks after bleaching
For intervention group: simvastatin injection in the sixth front teeth depth pocket with 1.2 mg for each inter proximal section, two weeks after bleaching
Sponsors
Vice chancellor for research, Mashhad University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
20 Years to 45 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: Female patients with 20 to 45 years old, with 4 to 6 mm space between front teeth of upper or lower gingival, controlled chronic periodontitis with Clinical Attachment Loss of 4 to 6 mm and without known allergy to simvastatin group medicines. Big tongue was not the cause of space. Exclusion criteria: Patients under systemic therapy with simvastatin group medicines, pregnant or breath feeding patients, sever periodontitis patients, smoker or alcoholic patients, patients with diabetes or immunosuppressive diseases.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Gingival index. Timepoint: Before the study and eight weeks after injection in control and intervention group. Method of measurement: According to bleeding index.;Clinical Attachment Loss. Timepoint: Before the study and eight weeks after injection in control and intervention group. Method of measurement: By Probe. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr Parasto Namdar
Mashad University of Medical Sciences
Outcome results
None listed