The blood flow of the macula, peripapillary and head of optic nerve.
Conditions
Interventions
Intervention 1: Intervention group: Two crocin tablets (15 mg) will be given into healthy participants in the project. Optical coherence tomography (OCT) imaging with angiography will be done before a
Sponsors
Mashhad University of Medical Sciences
Eligibility
Sex/Gender
All
Age
20 Years to 50 Years
Inclusion criteria
Inclusion criteria: The age of the volunteer should be between 20 and 50 Lack of systemic disease such as diabetes and hypertension Do not use systemic drugs Lack of any intraocular pathology No history of eye surgery
Exclusion criteria
Exclusion criteria: Any eye disease Age less than 20 or more than 50 History of eye surgery
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Macular blood flow. Timepoint: Before the intervention and two hours after taking 2 tablets of 15 mg crocin or placebo. Method of measurement: Coherence Optical Tomography Angiography (OCTA). | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood flow of peripapillary and optic nerve head. Timepoint: Before the intervention and two hours after taking two tablets of crocin or placebo. Method of measurement: Coherence Optical Tomography Angiography (OCTA). | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSeyed Ahmad Mohajeri
Mashhad University of Medical Sciences
Outcome results
None listed