Behcet's Disease. Behcet's disease
Conditions
Interventions
Intervention 1: Intervention group: Receiving one tablet of Crocin (15 mg) for three months. Intervention 2: Control group: Receiving one tablet of placebo for three months.
Sponsors
Mashhad University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: A patient with active Behcet's with ocular complications is selected according to the sun criteria, Patients with Behcet's syndrome with anterior, posterior, or diffuse eye involvement Long-term illness of the eye with active retinal vasculitis and macular edema Age over 18 years of both sexes A patient with Behcet's who is resistant (without improvement or exacerbation of the eye disease) or an approximate response (mild to moderate) to combination therapy (Psychosis and Steroids drugs) The ability to understand the overall study, interventions and possible complications
Exclusion criteria
Exclusion criteria: Patients with bilateral vision loss Patients receiving anti-TNF drugs such as thalidomide and pentoxifylline in the past three months. Patients with a history of immunosuppression include a viral infection such as tuberculosis Severe viral infections including hepatitis, pneumonia, pyelonephritis, or hepatitis in the last three months Pregnancy and breastfeeding Sensitivity to saffron alcohol consumption Cataract and other general items Diabetes
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Ocular Inflammation. Timepoint: Before Intervention, and after three months. Method of measurement: Fluorescein Angiography. | — |
Secondary
| Measure | Time frame |
|---|---|
| Best Corrected Visual Acuity. Timepoint: Before Intervention, and After Three Months. Method of measurement: Snellen Chart. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Seyed Ahmad Mohajeri
Mashhad University of Medical Sciences
Outcome results
None listed