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The effedt of vitmin E on Epilepsy

Evaluation of the vitamin E effect on oxidative stress markers of proteins and lipids in children with idiopathic epilepsy

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT2013041713051N1
Enrollment
30
Registered
2015-09-07
Start date
2013-06-23
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Epilepsy. Generalized idiopathic epilepsy and epileptic syndromes

Interventions

Intervention 1: The first group(control) was treated with oral capsules of 50000 units weekly, for 8 weeks. Intervention 2: the second group(intervention) was treated with oral capsules of 50000 units
Treatment - Drugs
The first group(control) was treated with oral capsules of 50000 units weekly, for 8 weeks
the second group(intervention) was treated with oral capsules of 50000 units weekly, for 8 weeks and pill of 100 IU vitamin E for a month

Sponsors

Shahid Sadoughi University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
2 Years to 14 Years

Inclusion criteria

Inclusion criteria: The study population included all children 14-2 years old that have been referred to pediatric neurology clinic of Yazd University of Medical Sciences. After taking a history and doing a physical examination and a specialty based on clinical judgment nervous children with idiopathic epilepsy were selected. Inclusion criteria: having idiopathic epilepsy According to the International Association; Having vitamin D deficiency; not taking vitamin E and D In the past two months Exclusion criteria: Having a history of allergy to drugs; Any underlying systemic disease that prevent Medications; strickening Symptomatic epilepsy; strickening Mental retardation

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Malone dialdehyde. Timepoint: Before Intervention and two months after that. Method of measurement: Spectrophotometry.;Carbonyl group. Timepoint: Before Intervention and two months after that. Method of measurement: Spectrophotometry.

Secondary

MeasureTime frame
The number of seizures. Timepoint: Before intervention and two months after that. Method of measurement: Questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Javad Mohiti

Shahid Saddughi University of Medical Sciences

mohiti@ssu.ac.ir+98 35 3820 3410

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026