General anesthesia. Other complications of anaesthesia
Conditions
Interventions
Intervention 1: Propofol, 2.5 mg/kg within 30 seconds
IV. Intervention 2: Etomidate, 0.3 mg/kg within 30 seconds
Treatment - Drugs
Propofol, 2.5 mg/kg within 30 seconds
Sponsors
Isfahan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: being aged from 18 to 45 years old; having no underlying diseases; being of ASA 1 classification; being an applicant for elective orthopedic surgery on upper and lower extremities; not being allergic to anesthetic drugs; not having any expected problems of the airway; receiving no narcotics or sedative drugs before the anesthesia and not being hemodynamic unstablility before the anesthesia. Patients who were a 4 grade after the induction of anesthesia and laryngoscopy, or their laryngoscopy were lasted longer than 30 seconds, or were not anesthetized using the mentioned dose of drugs and received higher doses, were excluded from the study.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Systolic blood pressure. Timepoint: Before intervention, at laryngoscopy time and 1 , 3 ,5 , 10 min after drug injection. Method of measurement: mm-hg, sphygmomanometer.;Diastolic bllod pressure. Timepoint: Before intervention, at laryngoscopy time and 1 , 3 ,5 , 10 min after drug injection. Method of measurement: mm-hg, sphygmomanometer.;Mean arterial pressure. Timepoint: Before intervention, at laryngoscopy time and 1 , 3 ,5 , 10 min after drug injection. Method of measurement: mm-hg, sphygmomanometer.;Heart rate. Timepoint: Before intervention, at laryngoscopy time and 1 , 3 ,5 , 10 min after drug injection. Method of measurement: ECG monitor.;O2 saturation. Timepoint: Before intervention, at laryngoscopy time and 1 , 3 ,5 , 10 min after drug injection. Method of measurement: Pulseoxymeter. | — |
Secondary
| Measure | Time frame |
|---|---|
| Hypotension. Timepoint: Other complications of anaesthesia. Method of measurement: mm-Hg, sphygmomanometer.;Hypertension. Timepoint: Other complications of anaesthesia. Method of measurement: mm-Hg, sphygmomanometer.;Tachycardia. Timepoint: Other complications of anaesthesia. Method of measurement: ECG monitor.;Bradycardia. Timepoint: Before intervention, at laryngoscopy time and 1 , 3 ,5 , 10 min after drug injection. Method of measurement: ECG monitor. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMehrdad Masoudifar
Isfahan University of Medical Sciences
Outcome results
None listed