Diabetes. Endocrine, Nutritional and Metabolic diseases
Conditions
Interventions
Intervention 1: This trial has 2 control group. The name of material that will used in this trial is Aloe vera pasteurized gel powder that contain Phytosterols? Sterols and Astanuls that explain
Prevention
This trial has 2 control group. The name of material that will used in this trial is Aloe vera pasteurized gel powder that contain Phytosterols? Sterols and Astanuls that explain the anti-diabet
The placebo that will used in this trial is Micro-crystalline cellulose that will Be purchased from Tehran Drug company? that is white and odorless. that is the first matter for capsules filling.
In the second group of the trial? participants will be consumed 500 mg capsules twice a day for 8 week. in the first of the trial a sample of blood will be taken from the Brachial vein for Meas
Sponsors
Vice Chancellor for Research, Birjand University of Medical Sciences
Eligibility
Sex/Gender
All
Age
35 Years to 65 Years
Inclusion criteria
Inclusion criteria: Major inclusion criteria to the study: have a Iranian nationality citizen? Have a consent to participate in the study? be between 35-65 years old ? Not in pregnant or breast feeding periods ? Do not have the sever experience of stress in 8 recent week ? Do not use the herbal supplements or aloe vera for lowering the blood sugar in the last 8 week? her/his BMI is between 20-30 ? In the 2-3 recent month; his or her HbA1c is between 4/6-7/5% ? The fasting blood glucose level is between 100-125 mg/dl? The level of HDL is less than 35 mg/dl? The level of Triglycerides is between 200-300 mg/dl? Do not detected the hepatic and renal failure? Do not have the elective surgery in next two month ? Is not affected the acute infections ? Is not going to go traveling more than a week ?Do not use any herbal supplement or drug for lowering the glucose of blood. Major exclusion criteria to the study: Be deterred from continuing to participate in the study? Become pregnant during the study ?Traveling more than a week? Had to be hospitalized for a while ? use another kind of herbal medicines during the study ? he or she is creating Significant changes of exercise, physical activity and diet,in the last 2 months? Have a major complication of extract in the middle of study ? Have severe stress such as the death of a close ; during the study? not to use the Extract more than one consecutive week? Him or her BMI is more than 30 ? Have a history of cardiovascular disease? Have a History of high cholesterol more than?300 His or her blood pressure is more than 130/60.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Glucose of blood. Timepoint: Before the trial? 30 and 60 days after that. Method of measurement: After sampling from brachial vein and send to the laboratoy of Imam Reza Hospital of Birjand, Determine the range of glucose of the blood by the Autoanalyzer and Pars azmoon test kit and its scale is mg/dl.;Lipids of blood. Timepoint: Before the trial? 30 and 60 days after that. Method of measurement: After sampling from brachial vein and send to the laboratory of Imam Reza Hospital of Birjand, Determine the range of lipids of the blood by the Autoanalyzer and Pars azmoon test kit and its scale is mg/dl.;HbA1c. Timepoint: Before the trial and 60 days after that. Method of measurement: After sampling from brachial vein and send to the laboratory of Imam Reza Hospital of Birjand, Determine the range of HbA1c of the blood by the Autoanalyzer and Pars azmoon test kit and its scale is %.;Depression. Timepoint: Before the trial and 60 days after that. Method of measurement: The score determine by the Beck depression Questionnaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSamane Alinejad Mofrad
Birjand University of Medical Science.
Outcome results
None listed