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Comparison between accelerated and conventional methods of Cornea collagen crosslinking in keratoconus patients

Comparison between accelerated and conventional methods of Cornea collagen crosslinking in prognosis of keratoconus patients, referred to Feiz hospital in 2013

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2013040912960N1
Enrollment
40
Registered
2013-05-11
Start date
2013-05-22
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

keratoconus. conical cornea

Interventions

Intervention 1: Usual 30-minute cross link surgery of keratoconus , using riboflavin and florescent light to stabilize corneal collagen and prevent progressive destruction of cornea. Intervention 2: A
Treatment - Surgery
Usual 30-minute cross link surgery of keratoconus , using riboflavin and florescent light to stabilize corneal collagen and prevent progressive destruction of cornea
Accelerated 5-minute cross link surgery of keratoconus , using riboflavin and uniform florescent light to stabilize corneal collagen and prevent progressive destruction of cornea

Sponsors

Isfahan University of Medical Sciences, Research and technology department
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Inclusion criteria: documented keratoconus patients who had refractive error higher than 2 diopters and were willing to participate in the study. Exclusion criteria: patients with poor compliance, who do not follow the post-operation orders precisely and confound the results, such as avoiding to take their medicine or not taking them correctly; patients who are affected with endophthalmitis or any other ophthalmic diseases after surgery; patients with systemic diseases such as collagen vascular disease.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Visual acuity. Timepoint: Before intervention, 6 months after intervention. Method of measurement: Snelen chart.;Keratometeric evaluation. Timepoint: Before intervention, 6 months after intervention. Method of measurement: Pentacam anterior SimK.;Topographic evaluation. Timepoint: Before intervention, 6 months after intervention. Method of measurement: Pentacam Scheimpflug imagery.;Refractory error. Timepoint: Before intervention, 6 months after intervention. Method of measurement: Auto refractive.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAlireza Peiman M.D.

Isfahan University of Medical Sciences

rahimi_ali1359@yahoo.com+98 31 1338 6836

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026