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Treatment of acne vulgaris

Topical Adapalene 0.1% Gel versus Topical Combination of (Tretinoin 0.025% and Erythromycin 4%) Gel in Treatment of AcneVulgaris

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2013040812758N2
Enrollment
36
Registered
2013-05-01
Start date
2009-10-01
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acne vulgaris. Acne vulgaris

Interventions

A split face method for application of treatment will used in which each patient instructed to use a combined gel formula of tretinoin 0.025% and erythromycin 4% on the right side of the face and ada
Treatment - Drugs

Sponsors

Iraqi Board for Medical Specializations
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Inclusion criteria: All patients with mild to moderate acne vulgaris will enrolled in the study. All patients must without any systemic and / or topical treatment for at least 2 months before starting the study. Exclusion criteria: Patients excluded from the study were those with severe acne, nodulocystic acne, patients with systemic diseases, pregnant and lactating women.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Change in acne scoring.(mild,moderate,severe)Mild acne in which the count of pustules is less than 20 and the count of papules is less than 10. Timepoint: Each patient was instructed to use the same amount of both gels (finger tip method), ½ hour in the 1st night then wash and increase the time by ½ hour in the successive nights till reach 8 hours; thereafter to keep the applications till morning. The duration of therapy was 6 weeks and follow up for another 6weeks. Method of measurement: The clinical evaluation was done every 3 weeks by 2 dermatologists; the assessment was carried out by counting the inflammatory lesions (papules and pustules) and watching any local side effects.

Secondary

MeasureTime frame
The satisfaction of the patient with the treatment. Timepoint: The clinical evaluation was done every 3 weeks. Method of measurement: The satisfaction of the patients to the treatment is classified into:1- Full satisfaction.2- Partial satisfaction.3 - No satisfaction.

Countries

Iraq

Contacts

Public ContactDr.Husam Ali Salman

Department of Dermatology-Baghdad medical college

husjob2000@yahoo.com00

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026