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Randomized Double-blind Placebo Controlled Trial of Topical Platelet Lysate hydrogel in patients with anal fissure referee to colorectal research center of shiraz medical university of medical sciences.

Randomized Double-blind Placebo Controlled Trial of Topical Platelet Lysate hydrogel in patients with anal fissure referee to colorectal research center of shiraz medical university of medical sciences.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT201304079936N4
Enrollment
82
Registered
2013-07-02
Start date
2013-02-03
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Fissure. Fissure and fistula of anal and rectal regions

Interventions

Intervention 1: The rectul drug will be used once daily in control group. Intervention 2: the platelet gel will be used once daily transrectaly in Intervention group.
Treatment - Drugs
The rectul drug will be used once daily in control group.
the platelet gel will be used once daily transrectaly in Intervention group

Sponsors

Shiraz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria:1 )Patient with acute and chronic anal fissure. 2) Patient without previous history of peri-anal fistula. 3) Patient without previous history of peri-anal abscess. 4) Patient without previous history of IBD, radiation, STD, TB Chemotherapy. 5) Patient without previous history of hemorrhoidectomy or peri-anal procedure. 6) Patient without previous history of migraine. 7) Patient without previous history of no pregnant. 8) Patient without previous history of anterior or posterior midline fistula. 9) Patient without previous history of IHD.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Treatment of fissure. Timepoint: Two weeks after initial treatment. Method of measurement: Exam by colorectal surgeon and complete the form.—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAkram Jamshidzadeh,pharm.D PhD

Shiraz University of pharmacy, Shiraz University of Medical Sciences

colorectal2@sums.ac.ir+98 71 1230 6972

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026