The Comparison of the Effect of Chlorhexidine Gluconate 2% with Transdermal Nitroglycerine Ointment 2% in Prevention of Phlebitis Due to Catheterization.

The Comparison of the Effect of Chlorhexidine Gluconate 2% with Transdermal Nitroglycerine Ointment 2% in Prevention of Phlebitis Due to Catheterization

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT201304077494N5

Enrollment

100

Registered

2013-09-04

Start date

2013-04-04

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

phlebitis. Phlebitis and thrombophlebitis of other sites

Interventions

Intervention 1: The intervention group Nitroglycerin Ointment, alcohol): After selecting the desired vein and disinfected with 70% Ethanol and paste the catheter was fixed to the skin. The distal port

Treatment - Drugs

The intervention group Nitroglycerin Ointment, alcohol): After selecting the desired vein and disinfected with 70% Ethanol and paste the catheter was fixed to the skin. The distal portion of the cathe

Intervention group and 2% chlorhexidine solution: This solution contains alcohol, which is 0.5% chlorhexidine solution to disinfect the area as cotton impregnated catheters are used. After selecting a

Eligibility

Sex/Gender

All

Age

20 Years to 65 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria included age over 20 years; having ordered intravenous catheterization; the patient's consent; the patient having to be alert and cooperative. Exclusion criteria included patients with immune deficiency and anemia; drugs recipient safety; and cardiovascular disease; skin disease; patients receiving hypertonic substances; diabetes,; dialysis; and patients with underlying diseases such as leukemia, kidney disease, chronic lung and liver; and receiving medications such as antibiotics, amiodarone, ranitidine, diazepam, phenytoin and corticosteroids; pregnant women; nursing mothers; people with headaches; glaucoma or increased intracranial pressure; hypotension (systolic pressure less than 100 mm Hg); hypertension (pressure more than 180 mm Hg); and a blood transfusion is administered.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Phlebitis. Timepoint: Before and during the study - the first to the 3th day of hospitalization. Method of measurement: checklist.	—

Secondary

Measure	Time frame
Prevention of phlebitis. Timepoint: post and every day until the 3th day. Method of measurement: phlebitis scale.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Mohamad Ali Heydari Gorj

Mazandaran University of Medical Science

heydarigorji@yahoo.com+98 15 1226 7342

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026