Condition 1: Hypotension. Condition 2: hypoxemia. Condition 3: Acute lung injury. Other specified disorders of circulatory system in diseases classified elsewhere
Conditions
Interventions
Intervention 1: In the intervention group, torniquet is inflated up to 20 mmHg higher than systolic blood pressure for 5 minutes. This procedure is repeated for three times with five min rest between
Treatment - Other
In the intervention group, torniquet is inflated up to 20 mmHg higher than systolic blood pressure for 5 minutes. This procedure is repeated for three times with five min rest between inflations.
In placebo group, torniquet in placed on the contralateral thigh but not inflated.
Sponsors
Tehran University of Medical Scienes
Eligibility
Sex/Gender
All
Age
18 Years to 149 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: elective cases of lower extremity fractures candidate of surgery with torniquet inflation more than 1 hr and ASA physical status I-III. Exclusion criteria: head/chest trauma; contra lateral fracture; deep sedation required (more than 1 mg midazolam); inadequate level of spinal anesthesia; High spinal anesthesia and addict patients.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Blood pressure. Timepoint: Before cuff inflation and after cuff deflation in 10 min intervals up to 30 min. Method of measurement: mmHg.;Heart rate. Timepoint: Before cuff inflation and after cuff deflation in 10 min intervals up to 30 min. Method of measurement: ECG monitoring.;Arterial oxygen saturation. Timepoint: Before cuff inflation and after cuff deflation in 10 min intervals up to 30 min. Method of measurement: Pulse oximetry. | — |
Secondary
| Measure | Time frame |
|---|---|
| IL-10. Timepoint: Before cuff inflation and after cuff deflation. Method of measurement: ELISA. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactFatemeh Jamshidi
Tehran University of Medical Sciences
Outcome results
None listed