Depression. Depressive episode
Conditions
Interventions
Intervention 1: Adding folic acid (5mg/d) to the therapeutic diet (citalopram) in patients with depression, for 4 month in interventions. Intervention 2: Adding plasbo to the therapeutic diet (citalo
Treatment - Drugs
Adding folic acid (5mg/d) to the therapeutic diet (citalopram) in patients with depression, for 4 month in interventions.
Adding plasbo to the therapeutic diet (citalopram) in patients with depression, for 4 month in controls.
Sponsors
Kermanshah University Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 100 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: patients' age>18years; having diagnosis of depression (DSM.IV.TR). Exclusion criteria: IQ less 70; schizophrenia; major medical or neurological disorders; pregnancy; any contraindications for using folates; wight lower than 30 kg; gastric or renal disorders; use of supplements such as B vitamins; chronic infections; anemia.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Response to trapy. Timepoint: At the beginning of study, 2 weeks later, 1 month then, After 2 months, after 3 months. Method of measurement: Beck Standard Inventory. | — |
Secondary
| Measure | Time frame |
|---|---|
| Response to trapy. Timepoint: At the beginning of study, 2 weeks later, 1 month then, After 2 months, after 3 months. Method of measurement: Beck Standard Inventory. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMaryam Pasha Abadi
Kermanshah University of Medical Sciences
Outcome results
None listed