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Effect of oral vitamin D on serum pro-B- type natriuretic peptide in peritoneal dialysis patients.

Effect of oral vitamin D on serum pro-B- type natriuretic peptide in peritoneal dialysis patients.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT201303252417N12
Enrollment
84
Registered
2013-04-06
Start date
2012-04-20
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

end stage renal disease. Chronic kidney disease, stage 5

Interventions

Intervention 1: Pearl vitamin D 50000 units, manufactured by Zahravi Pharmaceutical Company. 1 perl in week. If serum vit D less than 10ng/mL for 12 weeks. If serum vit D 10-30ng/mL for 8 weeks. Inter
Treatment - Drugs
Placebo
Pearl vitamin D 50000 units, manufactured by Zahravi Pharmaceutical Company. 1 perl in week. If serum vit D less than 10ng/mL for 12 weeks. If serum vit D 10-30ng/mL for 8 weeks.
Placebo pearl, manufactured by Zahravi Pharmaceutical Company. 1 perl in week. If serum vit D less than 10ng/mL for 12 weeks. If serum vit D 10-30ng/mL for 8 weeks.

Sponsors

Vice Chancellor for Research, Isfahan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: 1- Minimum duration of peritoneal dialysis for 3 months. 2- No treatment with vitamin D. 3- Patient satisfaction. Exclusion criteria: 1- History of malignancy. 2- History of myocardial infarction or heart failure in 3 months ago. 3- Serum level of vitamin D more than 30ng/m. 4- Calcium-phosphorus product more than 55.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Serum vitamin D level. Timepoint: Baseline, at the end of the study. Method of measurement: ng/mL.;Adequacy of dialysis. Timepoint: Baseline, at the end of the study. Method of measurement: software.;Serum Pro BNP level. Timepoint: Baseline, at the end of the study. Method of measurement: pg/mL.

Secondary

MeasureTime frame
Serum calcium level. Timepoint: Baseline, at the end of the study. Method of measurement: mg/dL.;Serum Parathormon level. Timepoint: Baseline, at the end of the study. Method of measurement: pg/dL.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Mojgan Mortazavi

Isfahan University of Medical Science

mortazavi@med.mui.ac.ir+98 31 1668 5555

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026