Skip to content

Comparison of long term efficacy of dextrose prolotherapy with hyalgan in knee Osteoarthritis

Comparison of long term efficacy of dextrose prolotherapy with hyalgan in knee Osteoarthritis

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2013031712831N1
Enrollment
110
Registered
2013-08-28
Start date
2013-06-11
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

knee OA.

Interventions

Intervention 1: intervention:in prolotherapy group we use ,9cc of 20% dextrose + 1cc lidocaine in strill condition & in knee joint space. Intervention 2: control: we use prepared vial of 2 cc hyalgan
Treatment - Drugs
intervention:in prolotherapy group we use ,9cc of 20% dextrose + 1cc lidocaine in strill condition & in knee joint space
control: we use prepared vial of 2 cc hyalgan in strill condition & in knee joint space

Sponsors

Army University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
50 Years to 90 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: age more than 50 years old; cripitation or morning stiffness less than 30 min & radiologic criteria of OA. Exclusion criteria: diabetes mellitus; other joint disease ( RA,...); surgery in knee; fx history;recent corticosteroid injection; immunosuppression and massive knee effusion.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Pain severity (pain score). Timepoint: 1 week, 1 month, 3 month , 8 month and 12 month. Method of measurement: VAS ruller.;Knee joint range of motion. Timepoint: 1 week, 1 month, 3 month , 8 month and 12 month. Method of measurement: goniometr.;Quality of life. Timepoint: 1 week, 1 month, 3 month and 8 month. Method of measurement: WOMAC questionary.

Secondary

MeasureTime frame
Infection. Timepoint: 1 week, 1 month, 3 month , 8 month and 12 month. Method of measurement: physical exam.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Masoumeh Bahrami Asl

Army University of Medical Sciences

masoomehbahrami@yahoo.com; m.bahrami.asl@gmail.com+98 21 8833 7915

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026