Iodine supplementation and iodine nutrition in lactating mothers and their breast-fed infants

Evaluation of the effects of two dose of iodine supplements on lactating mothers’ and breast-fed infants’ iodine nutrition status and comparing to formula-fed infants: From birth to one year

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT201303164794N8

Enrollment

208

Registered

2013-05-20

Start date

2013-06-22

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

iodine deficiency.

Interventions

Intervention 1: Intervention Groups: Supplements containing 150 and 300 micrograms iodine. Intervention 2: Control Group: Placebo.

Placebo

Intervention Groups: Supplements containing 150 and 300 micrograms iodine

Control Group: Placebo

Eligibility

Sex/Gender

Female

Age

15 Years to 45 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: lactating mother; full-term infants (37-42 weeks) with normal birth weight (2500-4200 g); neonate with age 3-5 days Exclusion criteria:Thyroid diseases in lactating mothers and their infants; Taking thyroid medications; using self-order iodine containing supplements; using iodinated antiseptics; neonate hypothyroidism

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Urinary iodine concentration in breast milk-fed infants. Timepoint: 3-5 days, 1, 2, 4, 6, 9, and 12 months after birth. Method of measurement: Acid- Digestion.	—

Secondary

Measure	Time frame
Urinary iodine concentration in lactating mothers. Timepoint: 3-5 days, 1, 2, 4, 6, 9, and 12 months after delivery. Method of measurement: Acid Digestion.;Breast milk iodine concentration. Timepoint: 3-5 days, 1, 2, 4, 6, 9, and 12 months after delivery. Method of measurement: Acid Digestion.;Urinary iodine concentration in formula-fed infants. Timepoint: 3-5 days, 1, 2, 4, 6, 9, and 12 months after birth. Method of measurement: Acid Digestion.	—

Measure

Time frame

Urinary iodine concentration in lactating mothers. Timepoint: 3-5 days, 1, 2, 4, 6, 9, and 12 months after delivery. Method of measurement: Acid Digestion.;Breast milk iodine concentration. Timepoint: 3-5 days, 1, 2, 4, 6, 9, and 12 months after delivery. Method of measurement: Acid Digestion.;Urinary iodine concentration in formula-fed infants. Timepoint: 3-5 days, 1, 2, 4, 6, 9, and 12 months after birth. Method of measurement: Acid Digestion.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactProf. Fereidoun Azizi

Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences

azizi@endocrine.ac.ir+98 21 2243 2500

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 22, 2026